Community-acquired, healthcare-associated and nosocomial infection was 27%, 7% and 66%, respectively, and mortality rate was 31%, 14% and 27%, respectively.
The most common isolated pathogen was CNS (25%) followed by Klebsiella (16%) and E.coli (14%) with the 30-days mortality rate of 36%, 35% and 27%, respectively. The 30-days mortality rate was highest for Acinetobacter selleckchem (50%) and Enterococcus (50%). Presence of systemic inflammatory response syndrome (SIRS) criteria (35% vs. 15%, p = 0.02) or high MELD score (66% vs. 11% for MELD ≥ 20 vs. <20, p < 0.001) were significantly associated with the 30-days mortality rate. High MELD score and site of infection (pneumonia vs. others) were significant variables in multivariable model. Conclusion: The risk of morality was high in cirrhotic patients, especially with high MELD score and pneumonia. Key Word(s): 1. Bactremia; 2. Cirrhosis; 3. Mortality; Presenting Author: MALAY SHARMA Saracatinib ic50 Additional Authors: CHITRANSHU VASHISHTHA Corresponding Author: MALAY SHARMA Affiliations: Jaswant Rai Speciality Hospital; Insitute of Liver & Biliary Sciences Objective: Endoscopic ultrasound (EUS) has important diagnostic and therapeutic utility in different situations in patients with portal hypertension. Methods: A total of 254 patients of portal hypertension remained under follow up at the endoscopic unit from Sep. 2005 to March 2013 at a tertiary care centre. EUS and hemodynamic
evaluation was done in all cases of ectopic varices (fundal duodenal and rectal varices).
EUS was also useful for diagnosis of endoscopically inevident varices at various locations. EUS guided therapy was done in selected situations. Results: A total of 97 cases underwent EUS during this period. EUS was done for hemodynamic evaluation of 81 cases of gastric, duodenal and rectal varices. In majority of cases the inflowing and outflowing perforators to the ectopic varices were identified. After the hemodynamic evaluation the modality of selection included banding of duodenal and rectal varices close to the inflowing perforators. Glue injection was given for gastric varices and EUS was done some time PtdIns(3,4)P2 during the follow up either before or after glue injection. EUS was useful in detection of small esophageal varices, and endoscopically inevident ectopic varices in 21 cases. 8 patients underwent EUS guided therapy. Conclusion: EUS is important as a diagnostic aid for various situations in portal hypertension in emergency or elective situations. EUS guided interventions may be a useful therapeutic option for selected situations in bleeding. Key Word(s): 1. EUS; 2. Varices; 3. Choledochal varices ; 4. Therapy; Sr. No. Indication Result 1. Hemodynamic evaluation of variccs 81 (i) Fundal/gastric 50 (ii) Duodenal 9 (iii) Rectal 22 2. Diagnosis of varices 21 (i) Small Esophcagal 4 (ii) Fundal/ gastric/ 8 (iii) Duodenal 3 (iv) Rectal 6 3.