“
“Arjunolic acid (AA), a triterpenoid, was isolated from the ethyl acetate and methanol extracts of Terminalia arjuna core wood. The purity of AA was analysed by its melting point, FT-IR and NMR spectroscopy analyses. BEZ235 In vitro cytotoxicity

was assessed using Ehrlich ascites carcinoma (EAC) and Dalton’s lymphoma (DAL) cell lines by incubating with different concentrations of AA. The cancer cell death percentage at 100 mu g concentrations of AA ranged between 66% and 70% on the DAL and EAC cell lines, respectively. This infers that AA causes considerable membrane damage to cancer cells.”
“BACKGROUND

Cellulite is characterized by alterations in the relief of the skin surface. Magnetic resonance imaging (MRI) is recognized as a reliable technique for measuring adipose volume according to body site selleck inhibitor and for the visualization

of the subcutaneous structures.

OBJECTIVE

To compare subcutaneous tissue in areas with and without cellulite on the buttocks of same subjects using a noninvasive technique.

METHODS AND MATERIALS

Thirty female patients with cellulite on the buttocks underwent MRI. An area with cellulite and another without cellulite on the contralateral buttock were selected. Two soft gelatin capsules of different sizes were used as skin markers to differentiate the areas with and without cellulite.

RESULTS

Fibrous septa were visualized in 96.7% of the area with cellulite depressions; most of them were ramified (73.3%) and presented a high-intensity signal on T2 images (70%). All fibrous septa found in the examined areas were perpendicular to the skin surface. The average fibrous septa thickness was 2.18 +/- 0.89 in the area with cellulite and 0.27 +/- 0.64 in the area S63845 order without cellulite.

CONCLUSION

Results of the MRI analysis showed that cellulite depressions on the buttocks were significantly associated with the presence of underlying fibrous septa.

The authors have

indicated no significant interests with commercial supporters.”
“A review of some regression models commonly used in respiratory health applications is provided in this article. Simple linear regression, multiple linear regression, logistic regression and ordinal logistic regression are considered. The focus of this article is on the interpretation of the regression coefficients of each model, which are illustrated through the application of these models to a respiratory health research study.”
“BACKGROUND

Botulinum toxin type A (BoNT-A) is frequently used to treat crow’s feet; the optimal dose for each toxin preparation should be established.

OBJECTIVE

To compare the efficacy and safety of three doses of BoNT-A with placebo to treat crow’s feet.