The t(1/2) of JI-101 with intravenous and oral route was found to be 1.75 +/- 0.79 and 2.66 0.13h, respectively. The CI and Vd by intravenous route Blasticidin S for JI-101 were found to be 13.0 +/- 2.62 mL/min/kg and 2.11 +/- 1.42 L/kg, respectively. The tissue distribution of JI-101 was extensive with rapid and preferred uptake into lung tissue. Overall, the oral bioavailability of JI-101 is 55% and the primary

route of elimination for JI-101 is feces.”
“AimWomen with imminent premature labor (IPL) are transported to a tertiary hospital equipped with neonatal intensive care unit (NICU) even during the night. However, there have been no extensive studies of the occurrence rate of night IPL. The aim of this study was to determine the occurrence rate of night IPL in an area with a population of 2 million.

Materials and MethodsA retrospective analysis was conducted using data collected by the Sapporo Obstetric System for Emergency Patients launched in October 2008, in which women, physicians, and ambulance staff who sought appropriate check details obstetric/gynecological facilities available in the night (19.00-06.00hours) were informed of candidate hospitals by coordinators through telephone consultation. This system covered the Sapporo area, which has a population of 2000000 and 17000 births annually. Approximately 14% and 86% of women received antenatal care at six and 35 obstetric

facilities with and without NICU, respectively, in this area. Night IPL was defined as a threatened premature labor and transport to one of six tertiary www.selleckchem.com/products/dinaciclib-sch727965.html hospitals with NICU between 19.00 and 06.00hours the next morning.

ResultsDuring a 4-year period from 1 October 2008 to 30 September 2012, the Sapporo Obstetric System for Emergency Patients received 15823 (mean +/- standard deviation) monthly telephone

consultations (range 114-218 per month). The monthly number of patients with night IPL was 3.0 +/- 2.2 (range 0-9 per month).

ConclusionsThe monthly number of cases of night IPL was around three among women who received antenatal care at obstetrics facilities without NICU in an area with a population of 2000000.”
“Maternal microchimerism (MMc) has been purported to play a role in the pathogenesis of autoimmunity, but how a small number of foreign cells could contribute to chronic, systemic inflammation has not been explained. Reports of peripheral blood cells differentiating into tissue-specific cell types may shed light on the problem in that chimeric maternal cells could act as target cells within tissues. We investigated MMc in tissues from 7 male infants. Female cells, presumed maternal, were characterized by simultaneous immunohistochemistry and fluorescence in situ hybridization for X- and Y-chromosomes Maternal cells constituted 0.017% to 1.9% of parenchymal cells and were found in all infants in liver, pancreas, lung, kidney, bladder, skin, and spleen.

Sixty patients were operated on during the study period. Spinal correction and fusion was performed by posterior approach. In six patients with a residual spinopelvic imbalance more than 15A degrees on lateral preoperative bending films, an anterior release of the thoracolumbar junction was performed on the same day, before posterior correction. Preoperative pelvic obliquity (PO) ranged from 4A degrees to 44A degrees (mean 21.6A degrees). Postoperative pelvic obliquity ranged from 0A degrees to 14 (mean 4.6A degrees). No significant loss of correction was noted at the last IPI-145 Angiogenesis inhibitor follow-up. One patient died 3 months after the initial procedure due to respiratory Selleck CA4P compromise.

11 patients had early postoperative infections of the posterior

approach.

Despite a high rate of infectious complications, optimal correction of pelvic obliquity requires extension of spinal instrumentation to the pelvis. Spinopelvic fixation remains a difficult challenge in neurological patients with hypotrophy. We think that pelvic fixation with the “”T construct”" did provide effective and improved spinal stabilization in these patients, while reducing the need for a postoperative cast or brace. As a result, patients had a favourable postoperative course with early mobilization and return to a comfortable sitting position.”
“Essential oils (EOs) of Achillea millefolium, Myrtus communis, Rosmarinus officinalis, Helichrysum italicum, Foeniculum vulgare Autophagy Compound Library in vitro and Lavandula angustifolia were analysed with GC-FID and GC-MS in order to define their aromatic profiles and then their toxicity and repellent activity against Sitophilus zeamais Motsch. (Coleoptera Dryophthoridae) with specific bioassays were evaluated. Results from topical applications on insects showed that all EOs had variable and significant insecticidal activity. Mortality rate never exceeded 76%. Results of repellency tests are indicated for M. communis and L. angustifolia EOs, displaying high repellent activity

to S. zeamais adults.”
“We prospectively compared surgical reduction or fusion in situ with posterior lumbar interbody fusion (PLIF) for adult isthmic spondylolisthesis in terms of surgical invasiveness, clinical and radiographical outcomes, and complications.

From January 2006 to June 2008, 88 adult patients with isthmic spondylolisthesis who underwent surgical treatment in our unit were randomized to reduced group (group 1, n = 45) and in situ group (group 2, n = 43), and followed up for average 32.5 months (range 24-54 months). The clinical and radiographical outcomes were compared between the two groups.

The average operative time and blood loss during surgery showed insignificant difference (p > 0.05) between two groups.

They were divided into 2 groups: patients with diverticulosis and patients without diverticulosis. Their demographic and clinical characteristics, colonic examination findings, and peritonitis data were compared and analyzed.

Results: GANT61 manufacturer 104 Chinese patients received 110 colonoscopies and 51 barium enema examinations. 25 patients (24.0%) had colonic diverticulosis. Patients with diverticulosis were older (65.4 +/- 14.7 vs 58.4 +/- 14.0 years, p = 0.033). The most common site of involvement of diverticulosis was the ascending colon (56%). 128 episodes of enteric peritonitis were recorded in 49 patients. Compared with patients without enteric peritonitis, more patients in the enteric peritonitis group

had diverticulosis (38.8% vs 10.9%, p = 0.001) and diverticulosis most often involved the ascending colon (20.4% vs 7.3%, p = 0.082). Multivariate logistic regression analysis showed that the presence of diverticulosis (hazard

ratio 5.17, 95% confidence interval 1.86 – 14.40; p = 0.002) and diverticulosis involving the ascending colon (hazard ratio 6.89, 95% confidence interval 1.43 – 33.32, p = 0.016) were independent risk factors for the development of enteric peritonitis. Enteric peritonitis in patients with diverticulosis had a higher but nonsignificant treatment failure rate (26.9% vs 18.4%, p = 0.282).

Conclusion: In this selected cohort of PD patients with indications of colonic examinations, diverticulosis, especially involving the ascending colon, may be Natural Product Library price a risk factor for the development of enteric Transmembrane Transporters inhibitor peritonitis. Colonic diverticulosis does not appear

to affect the outcome of enteric peritonitis. Further studies are warranted to determine ways to prevent enteric peritonitis in PD patients with diverticulosis.”
“BACKGROUND: The impact of inoculation on performance and subsequent community structure is a critical question in gas biofiltration processes. Thus, the aim of this study is to evaluate the impact of inoculation on biofilters packed with an inorganic medium and fed with a gaseous mixture (oxygenated and sulphur compounds). RESULTS: Inoculated biofilters (BF1 and BF2 duplicates) exhibit higher overall removal performances and lower removal height (oxygenated: 100% at 50 cm and sulphur: 55% at 100 cm) than control biofilters (PC) (oxygenated: 94% and sulphur: 39% at 100 cm). The concentration of compounds was measured along the bed height using two sampling lines. For each biofilter, the evolution of removal efficiency as a function of height differs and depends on the line considered. At steady-state, a divergence is observed between the bacterial communities of BFs that exhibited a similar stratification pattern of removal efficiency. CONCLUSION: Inoculation of biofilters seems to bring enough diversity to allow the emergence of fitted species resulting in higher pollutants removal and to strengthen the heterogeneity of biodegradation activities distribution along the column height.

20, 0.51, and 0.29, respectively, in the patient group and 0.20, 0.45, and 0.35, respectively, in the control group. The allele frequencies were 0.456 and 0.428 for T allele for the patient group and control group, respectively and 0.543 and 0.572 for C allele for the patient and control group, respectively. The data between

the two groups selleck chemical were analyzed by chi-square test or Fisher’s exact test. Our results showed that there are no significant differences in genotype (P = 0.56) or in allele frequencies (P = 0.51) between the patient and the control group.

Conclusion. The HSD3B1 T/C polymorphism cannot be used as genetic marker for the risk for RSA in our Caucasian population.”
“BACKGROUND: Adsorption of puerarin on native resin polystyrene (PS) and oligo-beta-cyclodextrin-coupled matrix (PS-CDP) was studied for interactions between the adsorbents and the adsorbates. The sorption mechanism on PS-CDP was investigated using the isosteric heat approach and nuclear magnetic resonance (NMR) spectroscopy.

RESULTS: SRT2104 in vivo The equilibrium adsorption data of puerarin on the two

matrices PS and PS-CDP (polystyrene-based matrix before and after coupling by oligo-beta-cyclodextrin) in the temperature range 288-318 K were well fitted to the Freundlich adsorption isotherm model. The energetic heterogeneity of the media was observed based on the result that the values of isosteric enthalpy were quantitatively correlated with the fractional loading of puerarin adsorption. The more heterogeneous surface of PS-CDP compared with PS was attributed to the complexation between puerarin and beta-cyclodextrin (beta-CD). NMR studies validated the formation of an inclusion complex PXD101 puerarin/beta-CD.

CONCLUSION: Thermodynamic and NMR studies confirmed that multi-interaction cooperatively governed the isolation of puerarin from aqueous solution on PS-CDP matrix. (c) 2009 Society of Chemical Industry”
“Objective: To evaluate population-based data on incidence and efficiency of middle ear surgery.

Study Design: Retrospective review.

Setting: All otolaryngology departments in one federal

state in Germany.

Patients: All 1,037 middle ear surgeries performed in Thuringia in 2005.

Interventions: Middle ear surgery. Main Outcome Measure: Analysis of preoperative and postoperative audiometric results, preoperative diagnostics, and postoperative complications. Univariate statistical tests were used to analyze predictors for air-bone gap (ABG) improvement, complications, and need for resurgery. Population data were used to calculate incidences of middle ear diseases admitted for surgery and annual rates of middle ear surgeries.

Results: ABG improved after surgery for chronic otitis media without and with cholesteatoma, otosclerosis, trauma cases, or complication after acute otitis media/externa (p < 0.0001; p < 0.0001; p < 0.0001; p = 0.005; p = 0.004; respectively).

The relationship

between large artery characteristics and pathogenesis of OA has not been investigated and was the aim of this study.

Design: Large artery characteristics (i.e., aortic stiffness, brachial and central blood pressure (BP) variables) and bone marrow lesions (BMLs; measured by magnetic resonance imaging as a surrogate index of OA) were recorded in 208 participants (aged 63 +/- 7 years; mean +/- SD) with symptomatic knee OA. Relationships between find more large artery characteristics and BML were assessed by multiple regression adjusting for age, sex and body mass index.

Results: There was a high prevalence of BML presence in the study population (70%), but no significant difference between participants with and without BML for all large artery and BP variables (P>0.05 all). Furthermore, there were no significant relationships between BML size and aortic stiffness (r = -0.033, P = 0.71), central pulse pressure (r = 0.028, P = 0.74), augmentation index (r = 0.125, P = 0.14), brachial pulse pressure (r = 0.005, P = 0.95) or brachial systolic BP (r = -0.066, P = 0.44). When participants

were stratified according to high or low aortic stiffness, there was no significant difference between groups regarding the proportion of those with a BML (64% vs 70% respectively; P = 0.69).

Conclusions: INCB028050 cell line Variables indicative of large artery characteristics are not significantly correlated with BML size or presence in people with symptomatic knee OA. Thus, large artery characteristics may not have a causative influence in the development of OA, but this needs to be confirmed in prospective studies. Crown Copyright (C) 2013 Published by Elsevier Ltd on behalf of Osteoarthritis Research Society International. All rights reserved.”
“The antiradical power of the methanol extracts of olive pomace (Taggiasca cultivar) achieved by Gamma-secretase inhibitor high-pressure-high-temperature reactor were investigated using ABTS(center dot+) and DPPH center dot assays. The highest antioxidant activity was quantified at 90 min of contact time and 180 degrees C of extraction temperature

(64.19 +/- 0.16 mu g(TE)L(-1) and 15.80 +/- 0.62 mu g(DPPH) mu L-extract(-1)). The extract with high-antioxidant power resulted to be effective to counteract key aspects of cellular oxidation sensitive mechanisms and inflammation associated to vascular diseases. A linear correlation (p < 0.05) between total polyphenol contents and antioxidant capacity was given by the ABTS(center dot+) method (R-2 = 0.9184) and DPPH assay (R-2 = 0.7062).”
“Objective: Proteoglycan (PG) loss and surface roughening, early signs of osteoarthritis (OA), are likely preceded by softening of the ground substance and the collagen network. Insight in their relative importance to progression of OA may assist the development of treatment strategies for early OA.

The compaction properties of the co-processed mannitol-chitin mixture were found to be dependent upon the quantity of mannitol added to chitin, in addition to the granulation procedure used. Optimal physicochemical properties of the excipient, from a manufacturing perspective, were obtained using a co-processed mannitol-chitin (2: 8, w/w) mixture prepared by wet granulation (Cop-MC). Disintegration

time, crushing strength, and friability of tablets, produced from Cop-MC using magnesium EGFR tumor stearate as a lubricant, were found to be independent of the particle size of the prepared granules. The inherent binding and disintegration properties of the compressed Cop-MC are useful for the formulation of poorly compressible, high-strength, and low-strength active pharmaceutical ingredients. The ability to co-process alpha-chitin with crystalline mannitol allows chitin to be used as a valuable industrial pharmaceutical excipient.”
“QUESTIONS: P. aeruginosa infections are assumed to play a major role in the frequency of exacerbations and severity of chronic obstructive pulmonary disease (COPD). Colonisation with P. aeruginosa accelerates lung function decline, most probably due to more frequent exacerbations. In this retrospective study we aimed

to determine selleck chemicals the prevalence of colonisation with P. aeruginosa in COPD patients treated in a tertiary hospital centre.

METHODS: 112 patients diagnosed with COPD testing positive for P. aeruginosa in at least one respiratory sample during the study period (2004-2008) were retrospectively analysed to estimate GOLD stage-specific prevalences, colonisation patterns, morphology and antibiotic resistance profiles

of P. aeruginosa strains.

RESULTS: Colonisation with P. aeruginosa was present in all COPD stages, but prevalence significantly Nepicastat increased with disease severity (GOLD 1: 0.7%, GOLD 2: 1.5%; GOLD 3: 1.5%; GOLD 4: 2.6%; p = 0.0003). 41% of COPD patients with P. aeruginosa-positive respiratory samples were chronic carriers, of whom 8% had mucoid strains. Carriage of a mucoid strain was associated with advanced COPD stage GOLD 4 (p = 0.01). Resistance to cephalosporins was most frequently encountered and resistance to ciprofloxacin was found in more advanced stages of COPD.

CONCLUSIONS: Colonisation with P. aeruginosa was present in all COPD severity stages and colonisation with mucoid strains was more frequent in advanced COPD. Resistance to the only oral anti-pseudomonas antibiotic ciprofloxacin was more frequently encountered in severe COPD stages.”
“In terahertz quantum well infrared photodetectors, a built-in-charge-mediated regime transition of the electronic transport is thoroughly investigated. The very strong current discontinuity and negative differential resistivity behavior are explained in terms of band structure reorganizations.

Study design. Two calvarial defects, 5 mm diameter, were prepared in parietal bone. The left defects were filled with natural bovine bone mineral (NBBM) and the right defects were left untreated. The first group did not receive fluoxetine. The second group and the third group received

7.5 mg and 15 mg flouxetine, respectively, daily by gastric gavage. The animals were killed 8 weeks after surgery, and the amount of bone regeneration was evaluated using histometric analysis.

Results. The Pevonedistat in vitro defects showed dose-dependent increase in bone formation. The bone fill length had statistical significant differences between NBBM/flouxetine (15 mg) group and other groups (P < .05). The presence of the NBBM had positive effect on the bone formation in all groups in so far as the maximum amount

of the increasing effect was seen in those rats filled with NBBM that received 15 mg flouxetine (P < .05). The minimum bone length in fluoxetine-treated defects was seen in 7.5 mg defects (0.36 mm)

Conclusion. Fluoxetine may improve the amount of bone regeneration in the rat calvarial defects. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod this website 2009; 108: 22-27)”
“The optical transmission spectrum of [111](c) poled relaxor-based ferroelectric single crystal 0.93Pb(Zn1/3Nb2/3)O-3-0.07PbTiO(3) (PZN-0.07PT) was measured in the range of ultraviolet to near infrared. The optical absorption edge has been determined and

the wavelength dependence of the absorption coefficient was calculated. The direct energy gap E-gd=3.144 eV, indirect energy gap E-gi=2.915 eV, and phonon energy E-p=0.097 eV (or 782 cm(-1)) were determined based on the theory of band to band transitions. It was also confirmed by Raman spectra that the indirect transition for the [111](c) poled PZN-0.07PT single crystal is mainly due to the contribution of 780 cm(-1) phonon corresponding check details to the Nb-O-Zn bond stretching mode.”
“Objective. A tooth with a dentigerous cyst (DC) does not always erupt by marsupialization. The eruption duration and conditions of DC-associated premolars were examined to predict such eruption following marsupialization.

Study design. The eruption and conditions including depth, root formation, inclination, and eruption space were examined retrospectively in 21 DC-associated mandibular premolars using dental and panoramic radiograms.

Results. Fifteen of 21 premolars erupted half within 3 months and all 15 erupted completely within 10 months after marsupialization, without orthodontic traction. The age of the patients, tooth depth, and inclination were significantly different between the erupted and non-erupted groups, whereas there was no significant difference in the root formation or the eruption space between the 2 groups.

Conclusions. The successful eruption of a DC-associated premolar can be predicted within 3 months after marsupialization.

(C) 2010 American Institute of Physics. [doi: 10.1063/1.3483956]“
“Purpose: To evaluate a widely used nontunneled triple-lumen central venous catheter in order to determine whether the largest of the three lumina (16 gauge) can tolerate high flow rates, such as those required for computed tomographic Selleckchem NVP-LDE225 angiography.

Materials and Methods: Forty-two catheters were tested in vitro, including 10 new and 32 used catheters (median indwelling time, 5 days). Injection pressures were continuously monitored at the site of the 16-gauge central venous catheter hub. Catheters were injected with 300 and 370 mg of iodine per milliliter of iopamidol by using a mechanical

injector at increasing flow rates until the catheter failed. The infusion rate, hub pressure, and location were documented for each failure event. The catheter pressures generated during hand injection by five operators were also analyzed.

Mean flow rates and pressures at failure were compared by means of two-tailed Student t test, with differences considered significant at P < .05.

Results: Injections of iopamidol with 370 mg of iodine per milliliter generate more pressure than injections of iopamidol with 300 mg of iodine per milliliter at the same injection rate. All catheters failed in the tubing external to the patient. The lowest flow rate at which catheter failure occurred was 9 mL/sec. The lowest hub pressure at failure was 262 pounds per Sapitinib Protein Tyrosine Kinase inhibitor square inch gauge (psig) for new and 213 psig for used catheters. Hand injection of iopamidol with 300 mg

of iodine per milliliter generated peak hub pressures ranging from 35 to 72 psig, corresponding to flow rates ranging from 2.5 to 5.0 mL/sec.

Conclusion: YAP-TEAD Inhibitor 1 Stem Cells & Wnt inhibitor Indwelling use has an effect on catheter material property, but even for used catheters there is a substantial safety margin for power injection with the particular triple-lumen central venous catheter tested in this study, as the manufacturer’s recommendation for maximum pressure is 15 psig. (C) RSNA, 2009″
“Objectives: Botulinum toxin A (BTX-A) injection into the detrusor muscle has changed therapy options for patients with overactive bladder (OAB). However, in some patients, therapy fails or the effects of BTX-A decrease. The aim of this prospective study was to evaluate the incidence of BTX-A antibodies (BTX-A Abs) after injection of BTX-A and its clinical relevance. Methods: 31 patients (27 women, 4 men) were treated with BTX-A for OAB between January 2009 and August 2010. Eleven patients were treated once, 16 patients were treated twice and 4 patients were treated three times. Blood was collected before and 3 months after the BTX-A injection and BTX-A Abs were determined. Results: In 5 patients (16%) BTX-A Abs were detectable after the BTX-A injection. The BTX-A Ab titer was clearly positive in 1 patient (3.2%). This patient showed complete failure of BTX-A therapy. In 4 patients (13%) BTX-A Abs were slightly positive after the first BTX-A injection.

Our data demonstrated that blockade of NMDA or AMPA receptors could attenuate the BBB disruption in focal GW4869 price cerebral ischemia and suggest that ionotropic glutamate receptors are involved in part in BBB disruption.”
“Phloem-transported

signals play an important role in regulating plant development and in orchestrating responses to environmental stimuli. Among such signals, phloem-mobile RNAs have been shown to play an important role as long-distance signaling agents. At maturity, angiosperm sieve elements are enucleate, and thus transcripts in the phloem translocation stream probably originate from the nucleate companion cells. In the present study, a pumpkin (Cucurbita maxima) phloem transcriptome was used to test for the presence of common motifs within the promoters of this unique set of genes, which may function to coordinate 4SC-202 order expression in cells of the vascular system. A bioinformatics analysis of the upstream sequences from 150 Arabidopsis genes homologous to members of the pumpkin phloem transcriptome identified degenerate sequences containing CT/GA- and GT/CA-rich motifs that were common to many of these promoters. Parallel studies performed on genes shown previously

to be expressed in phloem tissues identified similar motifs. An expanded analysis, based on homologs of the pumpkin phloem transcriptome from cucumber (Cucumis sativus), identified similar sets of common motifs within the promoters of these genes. Promoter analysis offered support for the hypothesis that these motifs regulate expression within the vascular system. Our findings are discussed in terms of a role for these motifs in coordinating gene expression within the companion cell/sieve element system. Smoothened Agonist cell line These motifs could provide a useful bioinformatics tool for genome-wide screens

on plants for which phloem tissues cannot readily be obtained.”
“The melanocortin-4 receptor (MC4R) has important roles in regulating food intake, energy balance, and body weight in mammals. In pigs and cattle, MC4R mutations have been identified as genetic markers for growth and traits. Compared with abundant research conducted on other livestock species, little is known about mutations of the ovine MC4R gene. We investigated the effect of MC4R polymorphisms on birth weight and on 45-day weaning weight in 144 Hu sheep. Four single nucleotide polymorphisms (SNPs; g.1016 G/A, g.1240 T/C, g.1264 G/A, and g.1325 A/G) were identified in the 3′-untranslated region of Hu sheep MC4R by PCR-single-strand conformation polymorphism and DNA sequencing. A haplotype block, containing g.1240 T/C, g.1264 G/A, and g.1325 A/G, was constructed within the Hu sheep MC4R gene. Four SNPs were found to be significantly associated with 45-day weaning weight, while the haplotype block was significantly associated with birth weight. Hu sheep with the genotypes GG in g.1016 G/A or with the genotype CCAAGG in the haplotype block, had higher 45-day weaning weights.

Clusters are spherical and randomly distributed in the germanium film in epitaxial relationship with the diamond lattice. They exhibit a broad size distribution. By performing a careful selleck screening library x-ray diffraction analysis, we could find that 97% of Ge3Mn5 clusters have their c-axis perpendicular to the film plane while 3% exhibit in-plane c-axis. We could also show a

slight in-plane distortion of the Ge3Mn5 lattice leading to a reduction of uniaxial magnetic anisotropy. These observations are well confirmed by complementary superconducting quantum interference device and electron paramagnetic resonance measurements. (C) 2011 American Institute of Physics. [doi:10.1063/1.3531222]“
“Obesity has reached epidemic proportions in the USA. Consequently, there are an increasing number MRT67307 of potential organ donors that are obese, but would otherwise be appropriate donors for pancreas transplantation (PTx). This is a retrospective study of all PTx performed at Indiana University

between 2003 and 2009 (n = 308) comparing donors with body mass index (BMI) < 25, 25-29.9, and >= 30 kg/m2. Data included recipient and donor demographics, seven and 90-d graft loss, one-yr pancreas, kidney (for simultaneous pancreas and kidney transplant only) and patient survival, causes of graft loss and death, peak amylase and lipase, length of stay, readmissions, complications, HbA1C, and c-peptide. Of the 308 donors, 84 (27%) were overweight and 43 (14%) were obese. The overweight donors were significantly older, and the obese donors had

hypertension significantly more frequently than the other two groups. There were no significant differences in recipient transplant demographics. There was no significant difference in length of stay or 90-d readmissions, seven or 90-d pancreas graft loss, one-yr graft or patient survival, peak serum amylase or lipase, HbA1C, or c-peptide. The incidence of post-transplant Galardin technical, immunological, and infectious complications were similar. Although technically challenging, PTx of allografts from obese donors can be accomplished with similar results compared to normal BMI donors.”
“We show for the first time that collectively jammed disordered packings of three-dimensional monodisperse frictionless hard spheres can be produced and tuned using a novel numerical protocol with packing density phi as low as 0.6. This is well below the value of 0.64 associated with the maximally random jammed state and entirely unrelated to the ill-defined “”random loose packing”" state density. Specifically, collectively jammed packings are generated with a very narrow distribution centered at any density phi over a wide density range phi is an element of (0.6, 0.740 48 … ) with variable disorder.