The recipients were separated into two groups according to the low and high adjusted graft volumes. During the follow-up period (mean 55.6 months), the low-graft-volume group conferred greater risk of rejection, chronic change, glomerulonephritis, and graft loss than the high-graft-volume group (all p’s < 0.05). However, the frequency of T-cell infiltration, as evaluated in protocol biopsy, was not different between the two adjusted graft volume groups. In conclusion, the graft volume check details as the surrogate marker for nephron number should be

considered in kidney transplantation, especially in otherwise similar donor conditions.”
“Molecular genetic studies of self-incompatibility (SI) can be difficult to perform in non-model self-incompatible species. Recently, an Arabidopsis thaliana transgenic model was developed for analysis of the SI system that operates in the Brassicaceae by inter-species transfer of genes encoding the S-locus receptor kinase (SRK) and its ligand, the S-locus cysteine-rich (SCR) protein, which are the determinants of SI specificity in the stigma and pollen, respectively. This article reviews the various ways in which the many advantages of A. thaliana and the extensive tools and resources available

in this model species have allowed the use of transgenic self-incompatible SRK-SCR plants to address long-standing issues related to the mechanism and evolution of SI in the selleck inhibitor Brassicaceae. It also presents the unexpected results of a Selleckchem GNS-1480 candidate gene approach aimed at determining if genes related to genes previously reported to be involved in the SI response of Brassica and genes required for disease resistance, which exhibits many similarities to the SI response, are required for SI in A. thaliana. These various studies have provided a novel insight into the basis of specificity in the SRK-SCR interaction, the nature of the signalling cascade that culminates in the inhibition

of ‘self’ pollen, and the physiological and morphological changes that are associated with transitions between the outbreeding and inbreeding modes of mating in the Brassicaceae.”
“We have fabricated organic field-effect transistors (OFETs) with a highly oriented active layer of poly[(9,9-dioctylfluorenyl-2,7-diyl)-co-bithiophene] (F8T2), which was formed with the help of a photoaligned polyimide film. Photoalignment is an attractive technique for integrating OFETs with aligned active layers on the same substrate, because of its potential capability of two-dimensional alignment patterning. The F8T2 layer formed on the photoaligned polyimide film showed an absorption dichroic ratio greater than 15 after annealing at 285 degrees C.

International collaboration on how best to arrange and organize a training program in pediatric anesthesia and

intensive care is encouraged.”
“Background: Peritubular endothelium plays a key role in the development and progression of diabetic and nondiabetic chronic kidney disease. Renal injury in disorders of glucose metabolism may appear as early as in the stage of impaired glucose tolerance (IGT) and is accelerated by hypertension. The aim of our study was to investigate renal histology in rats with hypertension and IGT, with special emphasis on the peritubular endothelium.

Methods: Hypertension and IGT (H/IGT) were provoked in adult male Wistar rats by bilateral administration of methylglyoxal into the ventromedial selleck screening library hypothalamus. Immunohistochemistry

with anti-renin and anti-imidazolone antibodies and immunoelectron microscopy with anti-renin antibody were performed.

Results: H/IGT rats showed tubulointerstitial fibrosis as well as renin and imidazolone staining in the papillary region. The patterns of immunostaining for renin and imidazolone were similar to that of endothelium. On electron microscopy, peritubular capillary endothelial cells and to a less extent, tubular epithelial NU7441 order cells showed renin positivity.

Discussion: Impaired glucose tolerance complicated with hypertension leads to tubulointerstitial fibrosis in rat kidney. Imidazolone deposition and renin production in peritubular capillary endothelial cells may play a role in the development of tubulointerstitial fibrosis.”
“Objective: To evaluate the feasibility,

efficacy and safety of ultrasound-accelerated catheter-directed thrombolysis (UACDT) in the delayed treatment of lower extremity deep venous thrombosis (DVT).

Design: Twelve patients with unilateral iliofemoral or femoropopliteal DVT (mean symptom duration 92 +/- 44 days) were prospectively investigated.

Method: UACDT was performed using recombinant human tissue plasminogen activator delivered using the EKOS EkoSonic system. Stents were deployed if indicated by post-procedure venography. Follow-up comprised weekly duplex ultrasound for 1 month and monthly thereafter.

Results: Successful thrombolysis occurred in 11/12 limbs (92%; complete 6/12, partial 5/12) after GDC-0941 supplier a mean infusion time of 26 +/- 7 hours. 2/12 patients required angioplasty and stent insertion. At a mean follow-up of 9 (6-15) months, 10/11 (91%) veins were patent whereas 1/11 re-occluded at 2 months (patient with protein-C deficiency). 2/11 limbs developed symptoms/signs of post-thrombotic syndrome and 3/11 had developed deep vein reflux (duplex ultrasound). 2/12 patients experienced pen-catheter bleeding but no major hemorrhage or symptomatic pulmonary embolism occurred.

Conclusions: This preliminary evidence suggests that UACDT may be a safe and effective option for the delayed treatment of lower limb DVT. (C) 2013 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.

35%) and S. newport (26.31%). All Salmonella isolates were tested for their susceptibility to 12 selected antimicrobial agents by the agar diffusion method. 43 (75.43%) isolates were resistant to one or more antimicrobials. Out of 43 resistant Epigenetic Reader Do inhibitor Salmonella isolates, 17 (39.5%) showed multiple resistance to tow or more different antimicrobials. Resistance to tetracycline, sulfamides, trimethoprim and streptomycin was the most frequent. We found 17 different patterns of multiresistant strains. The high level of antibiotic resistance of Salmonella isolates in the present study showed the possible significance of chicken

meat as a source of multiple antimicrobial-resistant Salmonella for human infections and suggest more restricttions on the irrational use of antibiotics.”
“The value MK-2206 datasheet of defibrillation threshold testing (DFT) has been debated in recent years, especially with developments in the technology of manufactured defibrillators, most of which are capable of delivering high energies (35 Joules [ J]) and have programmable features such as tilt percentage and pulse width duration that increase the efficiency of biphasic shocks. The following is an unusual case of elevated DFT despite all attempts of invasive and noninvasive approachesit highlights the importance of performing DFT testing particularly when implantable cardioverter defibrillator is indicated for secondary prevention of sudden

cardiac death and the need for devices capable of delivering higher energies >35 J. (PACE 2012; 35:e179e181)”
“Purpose: To propose a preprocessing technique that increases the compressibility in reversible compressions of thin-section chest computed tomographic (CT) images and to measure the increase in compression ratio (CR) in Joint Photographic Experts Group (JPEG) 2000 two-dimensional (2D) and three-dimensional (3D) compressions.

Materials and Methods: This study had institutional review GW-572016 purchase board approval, with waiver of informed patient consent. A preprocessing technique that automatically segments pixels outside the body region and replaces their values with a constant

value to maximize data redundancy was developed. One hundred CT studies (50 standard-radiation dose and 50 low-radiation dose studies) were preprocessed by using the technique and then reversibly compressed by using the JPEG2000 2D and 3D compression methods. The CRs (defined as the original data size divided by the compressed data size) with and those without use of the preprocessing technique were compared by using paired t tests. The percentage increase in the CR was measured.

Results: The CR increased significantly (without vs with preprocessing) in JPEG2000 2D (mean CR, 2.40 vs 3.80) and 3D (mean CR, 2.61 vs 3.99) compressions for the standard-dose studies and in JPEG2000 2D (mean CR, 2.38 vs 3.36) and 3D (mean CR, 2.54 vs 3.55) compressions for the low-dose studies (P < .001 for all).

Isolates are classified into five groups based on capsular antigen (capA, B, D, E and F). Recently, a new valuable PCR-based method was introduced to determine the epidemiological correlation between P. multocida infection and existence of virulence genes including tbpA, pfhA, toxA and hgbB. However, this method is tedious and laborious. Thus, in the current study, we designed a reliable multiplex PCR method for rapid detection of virulence genes in P. multocida. Eighty seven strains of P. multocida isolated from various clinically healthy and infected hosts were examined by uniplex PCR method for each virulence associated

buy Autophagy Compound Library genes. Based on our improved and simplified multiplex PCR method, rapid detection of four virulence genes was accomplished. It is proposed that its implementation may benefit the epidemiological investigations. (c) 2009 Elsevier Ltd. All rights reserved.”
“From cultures of thermophilic soil fungus Humicola grisea var thermoidea, a delta-lactam derivative (3-(2-(4-hydroxyphenyl)-2-oxoethyl)-5,6-dihydropyridin-2( 1H)-one) that

displayed anti-allergic activity was isolated, which was predicted by in silico computational chemistry approaches. The in vitro anti-allergic activity was investigated by beta-hexosaminidase hypoxia-inducible factor cancer release assay in rat basophilic leukaemia RBL-2H3 cells. The delta-lactam derivative exhibited similar anti-allergic activity (IC50 = 18.7 +/- 6.7 mu M) in comparison with ketotifen fumarate (IC50 = 15.0 +/- 1.3 mu M) and stronger anti-allergic activity than azelastine (IC50 = 32.0 mu M). Also, the MTT cytotoxicity assay with RBL-2H3 cells showed that delta-lactam does not display Compound Library cytotoxicity at concentrations lower than 50 mu M. This study suggests that the delta-lactam derivative has the potential to be used as a lead compound in the development of anti-allergic drugs for clinical use in humans.”
“Objective: Acquiring contemporary data on prevalence and natural history of abdominal aortic aneurysms (AAA) is essential

in the effort to optimise modern screening programmes. The primary aim of this study was to determine the fate of a 65-year-old male population 5 years following an invitation to an aortic ultrasound (US) examination.

Methods: In this population-based cohort-study, men were invited to US examination at age 65, and were re-invited at age 70. Mortality, AAA repair, and risk factors were recorded. An AAA was defined as a diameter >= 30 mm, and a sub-aneurysmal aorta as 25-29 mm.

Results: In 2006-2007, 3,268 65-year-old men were invited, and 2,736 (83.7%) were examined. After 5 years, 24 had completed AAA repair (6 died within 0-4 years), an additional 239 had died, and 194 had moved. Thus, 2,811 70-year-old men were re-invited, and 2,247 (79.9%) were examined. The AAA prevalence increased from 1.5% at 65 to 2.4% (95% Cl: 1.8 to 3.0) at 70, and of sub-aneurysmal aortas from 1.

We evaluated global myocardial function, including myocardial performance index (MPI), on echocardiography in MS patients after remote mitoxantrone treatment.

Methods and Results: Consecutive patients (n = 50) treated with standard-protocol mitoxantrone from 2002 to 2010 in our center were identified. After exclusion of those who had died (n = 4; all noncardiac) or had developed interim cardiovascular disease or risk CBL0137 datasheet factors

(n = 3), 33 (mean age 49 +/- 11 years, 45% male, median follow-up 77 months, mean cumulative dose 72 mg/m(2)) of the remaining patients (77%) underwent 2-dimensional echocardiography. A comparison group of 17 age- and sex-matched control subjects were included. No significant differences occurred in standard echocardiographic parameters between groups. However, mean MPI (defined as isovolumic contraction time plus isovolumic relaxation EX 527 time (IVRT) divided by ejection time) was significantly higher in patients (0.51 +/- 0.12 vs 0.39 +/- 0.06; P = .02) owing to a significantly prolonged IVRT (81 +/- 25 vs 60 +/- 9 ms; P = .04). Overall MPI was >0.5 in 18 patients compared with none of the control subjects (54.5% vs 0%; P <

.001).

Conclusions: A subclinical form of global myocardial dysfunction reflecting primarily diastolic dysfunction may be present in MS patients after remote standard-dose mitoxantrone treatment.”
“BACKGROUND: The availability of suitable lung donors has remained a significant barrier to lung transplantation. The clinical relevance of an isolated positive Gram

stain in potential donor lungs, which occurs in >80%, is unclear. Low doses of lipopolysaccharide (LPS) have been protective in several models of ischemia-reperfusion injury through a pre-conditioning response. We sought to demonstrate that low-dose LPS is protective against subsequent lung ischemia-reperfusion injury.

METHODS: Pathogen-free Long-Evans rats were pre-treated with vehicle or LPS 24 hours before 90 minutes of ischemia and up to 4 hours of reperfusion. Lungs were assessed for vascular permeability, myeloperoxidase content, bronchoalveolar lavage inflammatory cell and cytokine/chemokine content, as well as nuclear translocation of nuclear factor kappa B (NF kappa B) and activator Selleckchem Luminespib protein-1 (AP-1), and interleukin-1 receptor-associated kinase-1 (IRAK-1) and stress-activated protein kinase (SAPK) activation.

RESULTS: Compared with positive controls, LPS pre-treatment resulted in reductions in vascular permeability (70%, p < 0.001), myeloperoxidase content (93%, p < 0.001), bronchoalveolar lavage inflammatory cells (91%, p < 0.001), and inflammatory cytokine/chemokine content (cytokine-induced neutrophil chemoattractant, 99%.p = 0.003; interleukin-1 beta, 72%, p < 0.0001; tumor necrosis factor-alpha, 76%, p < 0.0001), NF kappa B (86%, p < 0.001) and AP-1 (97%, p < 0.

Reference intervals CYT387 were differentiated by sex and by age in 90% and 42%, respectively. Laboratories reported eGFR in 35% and only when requested in 13%. eGFR was calculated by the

Modification of Diet in Renal Disease (MDRD) Study and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations in 88% and 12% of laboratories, respectively, and reporting was accompanied by information on the interpretation of values in 62%. Among nephrologists, 64% thought eGFR reporting useful, 29% were concerned with an excess of unnecessary requests for consultations and 95% expressed a favorable opinion of educational initiatives.

Conclusion: Our survey highlights the need for further improvement in serum creatinine measurement and reporting, and for coordinated interventions involving all major stakeholders.”
“The phenol amount of Lygodium japonicum extracted by the pressure-assisted

water extraction (PAWE) was noticeably increased to 12.8mg GAE/g when compared check details to the conventional extraction (9.3 mg GAE/g) (p < 0.05). The highest antioxidant activity was observed at Polygonum aviculare extracted by the PAWE, showing the lowest EC50 value of 0.09 mg/mL. The lowest minimum inhibitory concentrations (MIC99) of L. japonicum extracted by the PAWE were 2.59, 3.33, and 7.37 mg/mL, respectively, against Listeria monocytogenes, Salmonella Typhimurium, and Propionibacterium acnes. These results suggest that the PAWE can be an appropriate extraction method for enhancing biological and pharmaceutical properties of medicinal plants.”
“Background: Haemodialysis Epigenetics inhibitor patients are exposed to high levels of oxidative stress, perhaps contributing to increased rates of cardiovascular and malignant disease. In this context,

the body’s defence mechanisms against oxidative insult, including activity of the antioxidant enzymes superoxide dismutase (SOD) and glutathione peroxidase (GPx), are known to be deranged.

Methods: This randomised double-blind study assessed the effects of a novel micronutrient cocktail containing physiological doses of antioxidant vitamins and trace minerals on antioxidant enzyme activity in maintenance haemodialysis. Thirty-seven patients were randomised to receive placebo or micronutrient. SOD and GPx activity was analysed at baseline and after 6 months of treatment.

Results: SOD levels did not change in the treatment group but fell significantly (p=0.0443) in controls, while activity of GPx remained unchanged in controls but rose significantly (p=0.0123) in treated patients.

Conclusions: These results are consistent with a beneficial effect of the cocktail on antioxidant enzyme activity and may contribute to an indication for large-scale studies to assess clinical outcome measures.”
“BACKGROUND:

C-reactive protein (CRP), a marker of inflammation, plays a role in the pathophysiology of atherosclerotic events.

The short-term follow-up precluded a conclusion of statistically significant benefits from the shortening of the transportation and door-to-needle time.”
“Norwegian national policies have been distinguished by their focus on equity, contributing to comprehensive policies to reduce the social inequities in health(SIH). The-newly-adopted Public health act, which aims at reducing the SIH, endorses these acknowledgements while highlighting the importance of municipalities as the key actors in public health. Municipal obligations include inter-sectoral policies for health, health impact assessments (HIA), and the development of local health overviews. Against the background

of a system of local autonomy in Norway, this article illuminates whether, and how, municipal public health policies reflect national

priorities. Our data are based on one qualitative study, combining document content analysis and expert Selleckchem LDK378 interviews conducted in 2011, and one quantitative questionnaire sent to municipal chief administrative officers in 2011. Our ABT-263 order findings indicate a divide between national and municipal public health strategies. Many municipalities focus on life-style and health-care related measures. Only few municipalities acknowledge the social determinants of health and have implemented HIA and health overviews. Arguing for the importance of concerted multi-level action to reduce the SIH, we need to better understand the gap between national and municipal approaches. We thus suggest further research to illuminate the challenges and success factors faced at local levels. (C) 2013 Elsevier Ireland Ltd. All rights reserved.”
“Objectives: To review the reporting of key items of recruitment information in trial reports and estimate the number needed to screen to recruit one additional participant.

Study Design and Setting: Review of breast cancer trials published in the years 2003-2005, 2007, and 2008.

Results:

The search identified 1,570 potentially Volasertib eligible studies. After a random selection of 20% from each year and checking against inclusion criteria, a total of 207 studies were included in the review. Some items of information were well reported, such as the number included in the analysis. Sample size calculations were often not presented, but reporting is slowly improving. Who recruits participants and how many individuals were screened are often not reported. The median number needed to screen to recruit one additional participant was two (range, 1-593).

Conclusions: Without reporting the when, where, by whom, and how many of recruitment, trialists deny readers part of the contextual description they need to judge whether a trial’s results are applicable to their own situation. Trialists and journal editors need to be more diligent in following the reporting recommendations of the Consolidated Standards of Reporting Trials statement. (C) 2011 Elsevier Inc. All rights reserved.

Measurements on each fiber were obtained at baseline and were repeated after each set of 10 sterilization cycles for a total of 100 cycles. To measure resolution, the 1951 USAF Contrast Resolution Chart Target was used to subjectively identify the clearest image on the grid by two different operators. To measure distortion, three images of the distortion grid target were captured

with a digital camera and analyzed within Image Pro Plus Software. Light transmission was measured using a digital light click here meter at 50% and 100% transmission.

Results: There was no significant difference in resolution after 100 sterilization cycles between either Steris or Sterrad NX. Distortion changed by 8.7% and 11.2% for Steris and Sterrad NX, respectively. For Steris at 100% light transmission, baseline was 59 foot-candles

and this increased to 85 foot-candles after 100 cycles. For Sterrad NX at 100% light transmission, baseline was 50 foot-candles and this increased to 92 foot-candles after 100 cycles. Results were similar at 50%. There was no significant difference between groups at 50%, 100%, or between sterilization modalities.

Conclusion: The PolyScope fiber optic bundle appears durable after 100 cycles of sterilization with either Steris or Sterrad NX.”
“Amantadine is not thought to be effective for the treatment of swine-origin influenza virus (S-OIV) based on an analysis IPI 145 of genetic sequences of the M2 protein. However, the actual clinical efficacy of amantadine has not been well documented. Here, we were able to compare the efficacies of amantadine and neuraminidase inhibitors. Subjects consisted of 428 patients, including 144 with seasonal influenza (flu) identified between 2008 and 2009, and 284 with S-OIV identified between July 1 and November 30, 2009. Diagnosis of flu was established using a rapid diagnostic kit obtained commercially in Japan. Body temperature sheets were obtained from 95% of the S-OIV patients. Times required to recover normal body temperature were compared among subjects using different antiviral drugs. Genetic abnormalities in the M2 protein were also investigated

in 66 randomly selected subjects from within the patient pool. Overall, the average hours required to recover normal body temperature in LB-100 S-OIV patients treated with amantadine (160 cases), with oseltamivir (59 cases), or with zanamivir (65 cases) were 33.9 +/- A 20.7, 31.7 +/- A 16.0, or 36.3 +/- A 21.6, respectively. These differences were not statistically significant. The N31S abnormality was found in all 14 samples taken from the H3N2 patients and in all of the 23 samples taken from in S-OIV patients. However, this abnormality was not found in any of the 30 samples taken from seasonal H1N1 patients. Amantadine was found to be equally effective in treating S-OIV patients as neuraminidase inhibitors.

RESULTS: Oxygenation and dynamic compliance were significantly higher in the beta-2 group than in the control group. The beta-2 group revealed significantly higher levels of cyclic adenosine monophosphate

and high-energy phosphates in the donor lung after the inhalation than before it. Histologic findings revealed that the beta-2 group had less edema and fewer inflammatory cells.

CONCLUSION: Our results suggest that beta-2 adrenoreceptor agonist inhalation during the pre-procurement period may ameliorate IRI. J Heart Lung Transplant 2012;31:773-9 (C) 2012 International Society for Heart and Lung Transplantation. All rights reserved.”
“A mixture of alpha-dicarbonyl compounds generated from Maillard reaction (MR) model systems, comprising www.selleckchem.com/products/pexidartinib-plx3397.html of fructose with glycine (Fru-Gly) and lysine (Fru-Lys): glucose with glycine (Glu-Gly) and lysine (Glu-Lys); ribose with glycine (Rib-Gly) and lysine (Rib-Lys), were identified and quantified. alpha-Dicarbonyl compounds generated in the hexose models were predominantly glucosone and 3-deoxyglucosone (3-DG), with 3-deoxypentosone (3-DP) and pentosone being the major alpha-dicarbonyls

produced in the pentose models. Ethyl acetate extraction of model MRPs resulted in poor recovery of 2,3-diaminonaphthalene benzoquinoxalines of glucosone, 3-DG, pentosone, 3-DP and methylglyoxal (MGO), respectively. The temporal profiles of pentosone, 3-DP, glyoxal (GO) and MGO were similar in the pentose models, with maximum concentration occurring within 5 min. These four alpha-dicarbonyl AZD6094 compounds were higher (P<0.05) in Rib-Gly than in Rib-Lys MR systems.

The quantity of alpha-dicarbonyl compounds was affected by the interaction among the type of sugar and amino EVP4593 cost acid and the reaction time. The type of sugar is the most important factor that affected both the quantity and quality of alpha-dicarbonyl compounds produced in MR mixtures. (C) 2011 Elsevier Ltd. All rights reserved.”
“Aim We investigated if optimal surgical debulking increases tumor responsiveness to maintenance chemotherapy and improves survival in advanced ovarian cancer patients who previously attained a clinical complete response (CCR) to primary chemotherapy.

Materials and methods We retrospectively reviewed 75 advanced ovarian cancer patients, of whom 43 and 32 underwent optimal versus suboptimal cytoreduction, respectively. All patients exhibited a CCR following 6 cycles of paclitaxel and carboplatin and subsequently received maintenance chemotherapy (paclitaxel 135 mg/m(2); q21 days).

Results The median progression free survival (PFS) for the optimally debulked patients was 35 months, compared to 20 months for the suboptimal population (P = 0.003).

The films of the polymers were prepared by casting the polymer solution in dichloromethane. The polymers have been well-characterized by GPC, IR, and NMR techniques.

Thermal stabilities and decomposition behavior of the copolyimides were studied by DSC and TGA. The water contact angle values of the films indicate hydrophobic nature of the polymers. Thermal, flame retardant, mechanical, and surface properties of these polymers have been compared with the homopolyimide and with polyimides where polysiloxane is incorporated in the main chain. DSC revealed melting of the grafted siloxane chain at sub-ambient temperature and a glass transition corresponding to the main polymer chain above 200 degrees C. (c) 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012″
“Intraportal islet transplantation suffers from low efficiency caused QNZ NF-��B inhibitor by substantial islet mass loss after transplantation. How this process is regulated is

still unclear. Here, we show that NF-kappa B activation was detectable in islet grafts shortly after transplantation of porcine islets to diabetic NMRI nu/nu mice, and systemic NF-kappa B inhibition in transplanted animals significantly VX-809 cost prolonged islet graft survival. Proinflammatory cytokines alone did not cause evident cell death in pancreatic islet within 24 h, while the combination of cytokines with hypoxia resulted in a strong induction of cell death that could be blocked dose-dependently by a selective IKK-beta inhibitor. Under hypoxia, NF-kappa B activity impaired expression of antiapoptotic gene BCL-xL, c-FLIP and survivin. NF-kappa B activation in isolated Staurosporine solubility dmso islets was reduced by hypoxia in a time-dependent manner, accordingly, NF-kappa B activation in transplanted islets diminished by time. Our data indicate that, while NF-kappa B has an antiapoptotic role under normoxia, low oxygen conditions decrease its activity and transform it to a proapoptotic transcription factor in pancreatic islets. We conclude

that NF-kappa B inhibition represents a potential strategy to improve islet transplantation efficiency.”
“Objective : The aim of this study was to determine the association between cord blood adiponectin and leptin and early infant growth at one year in small for gestational age (SGA) and appropriate for gestational age (AGA) infants.

Study design: In this prospective study adiponectin and leptin concentrations were determined in cord blood of (i) AGA newborns (n=44) and (ii) SGA newborns (n=24). At one year of age, height and weight were measured. Linear regression analysis was used to determine which factors were associated with anthropometric measurements at the age of one year.