An alternative explanation is that the test is operator-dependent

An alternative explanation is that the test is operator-dependent and the ultrasonographers are not experienced or adequately trained to diagnose {Selleck Anti-infection Compound Library|Selleck Antiinfection Compound Library|Selleck Anti-infection Compound Library|Selleck Antiinfection Compound Library|Selleckchem Anti-infection Compound Library|Selleckchem Antiinfection Compound Library|Selleckchem Anti-infection Compound Library|Selleckchem Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|buy Anti-infection Compound Library|Anti-infection Compound Library ic50|Anti-infection Compound Library price|Anti-infection Compound Library cost|Anti-infection Compound Library solubility dmso|Anti-infection Compound Library purchase|Anti-infection Compound Library manufacturer|Anti-infection Compound Library research buy|Anti-infection Compound Library order|Anti-infection Compound Library mouse|Anti-infection Compound Library chemical structure|Anti-infection Compound Library mw|Anti-infection Compound Library molecular weight|Anti-infection Compound Library datasheet|Anti-infection Compound Library supplier|Anti-infection Compound Library in vitro|Anti-infection Compound Library cell line|Anti-infection Compound Library concentration|Anti-infection Compound Library nmr|Anti-infection Compound Library in vivo|Anti-infection Compound Library clinical trial|Anti-infection Compound Library cell assay|Anti-infection Compound Library screening|Anti-infection Compound Library high throughput|buy Antiinfection Compound Library|Antiinfection Compound Library ic50|Antiinfection Compound Library price|Antiinfection Compound Library cost|Antiinfection Compound Library solubility dmso|Antiinfection Compound Library purchase|Antiinfection Compound Library manufacturer|Antiinfection Compound Library research buy|Antiinfection Compound Library order|Antiinfection Compound Library chemical structure|Antiinfection Compound Library datasheet|Antiinfection Compound Library supplier|Antiinfection Compound Library in vitro|Antiinfection Compound Library cell line|Antiinfection Compound Library concentration|Antiinfection Compound Library clinical trial|Antiinfection Compound Library cell assay|Antiinfection Compound Library screening|Antiinfection Compound Library high throughput|Anti-infection Compound high throughput screening| appendicitis. Regardless inability to diagnose appendicitis by ultrasound in patients with peritonitis did not sway the clinician

away from surgical intervention. In this study, the sensitivity and specificity of ultrasound to detect free fluid and/or abscess was 0.82 and 0.83. Interpretation of this is limited without intra-operative quantification of fluid volume, as prior studies suggest a minimum of 100 mL to over 500 mL of fluid is necessary for an ultrasound to reveal fluid [16]. This retrospective study was not able to examine the utility of plain films in the management

of peritonitis because patients often keep their radiographs upon discharge. Our analysis also showed association between preoperative factors and outcome, but this observational study does not prove causality. Future research should aim to determine if correction of factors associated with mortality (such as fluid resuscitation to correct tachycardia and/or hypotension) might improve outcomes. The generalizability of NVP-BSK805 this study is also limited to adult patients at a find more tertiary care setting, as we did not include patients admitted to the pediatric ward or patients managed in district hospitals or health centers. Lastly, the definition of peritonitis, though standardized, assumes that all health care providers are adept at assessing the abdominal exam for guarding, rebound tenderness,

and rigidity. Conclusions ZD1839 clinical trial In our setting peritonitis is associated with an overall mortality rate of 15%. The most common causes are appendicitis and volvulus, and factors associated with death include abdominal rigidity, generalized (versus localized) peritonitis, hypotension, tachycardia and anemia. Future research should investigate whether preoperative correction of these factors improves survival. Acknowledgements We thank the UNC Project in Lilongwe, Malawi, and the UNC Division of Infectious Diseases for administrative assistance.

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