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Western countries, a more subtle scenario seems more likely: broad-scope PCS may be sold to the public under the banner of giving people choices, but without caring much about whether those choices are real and meaningful (Dondorp and De Wert 2010). The best way of challenging these possible scenarios is through investing in the counter scenario of PCS programmes in which the autonomy-objective is allowed to be a practice-shaping force, rather than just a banner or a slogan. Acknowledgements This research was supported by the Centre for Society and Genomics, funded by the Netherlands Genomics Initiative (project number: 70.1.070). Conflict of interest The authors declare that they have no conflict of interest. Open Access This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, ALK inhibitor cancer distribution, and reproduction in any medium, provided the original author(s) and source are credited. References ACOG (2011) ACOG Committee opinion no. 486: update on carrier screening for cystic fibrosis.

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