Microbiology and Molecular Biology Tipifarnib in vivo Reviews, 64:548–572. Rontó, G., Bérces A., Fekete, A., Kovács, G., Gróf, P., and Lammer, H. (2004). Biological UV

dosimeters in simulated space conditions. Advances in Space Research, 33: 1302–1305. Schuch, A. P., Guarnieri, R. A., Rosa, M. B., Pinheiro, D. K., Munakata, N., and Schuch, N. J. (2006). Comparisons of biologically effective doses of solar UV-radiation determined with spore dosimetry and spectral photometry in 2000–2003 at Southern Space Observatory, Brazil. Advances in Space Research, 37: 1784–1788. E-mail: pabulo@lacesm.​ufsm.​br First Results from Mars Simulator LISA R. Visentin1,2, G. Bertoloni2, M. D’Alessandro3, G. Galletta1 1Dipartimento di Astronomia, Università di Padova, Italy; 2Dipartimento di Istologia, Microbiologia e Biotecnologie Mediche, Università di Padova, Italy; 3INAF-Osservatorio Astronomico di Padova, Italy We present the first results obtained from experiments performed with the Martian simulator LISA (Laboratorio Italiano Simulazione Ambienti, Galletta et al., 2006, 2007). The research was carried

out at the University and Astronomical Observatory of Padua, Italy. LISA environmental chamber has been designed to simulate the conditions on the surface of planet Mars (atmospheric pressure, 6–9 Mb; temperature ranging from 133 to 293 K, atmospheric composition, 95% of carbon dioxide; strong UV radiation). We have studied the survival of the microorganisms exposed to the above described conditions. The microorganisms used in our experiments are bacterial 17-AAG solubility dmso strains belonging to the

genus Deinococcus, and to the endospore forming genera Bacillus and Clostridium (D’Angelo, 2007). Cellular suspensions or endospores suspensions were layered on sterile coverslip dehydrated under sterile air flux, introduced in dedicated plates and then exposed to the Martian condition inside the LISA chamber. One of our Bacillus strains has shown Megestrol Acetate a particular capability to survive in Martian conditions without screening by dust or other shields, in fact we Selleckchem PF-6463922 noticed a capability to survive (as endospores suspension) at least 4 h and in some cases to 28 h of Martian conditions, in the longest experiment we performed until now. We discuss the features of the experiments, our first results and the future tests to investigate the survival of lifeforms under Martian conditions. D’Angelo, G., (2007). Sopravvivenza di cellule e spore batteriche esposte a condizioni ambientali estreme. BSc Thesis, Dipartimento di Scienze Matematiche, Fisiche e Naturali, Università degli Studi di Padova. Galletta, G., Ferri, F., Fanti, G., D’Alessandro, M., Bertoloni, G., Pavarin, D., Bettanini, C., Cozza, P., Pretto, P., Bianchini, G., and Debei, S. (2006). S.A.M., the Italian Martian simulation chamber. Origins of life and evolution of the biosphere, 36: 625–627. Galletta, G., D’Alessandro, M., Bertoloni, G., Fanti, G., Danese, E., Pelizzo, M., Ferri, F., Pavarin, D., Bettanini, C., Bianchini, G., Debei, S. (2007).