Herein, we report a unique presentation in a 43-year-old man with a medical history of diabetes and high blood pressure which served with dyspnoea and permanent pain inside the correct knee and ended up being discovered having intense limb ischaemia and diabetic ketoacidosis. Our instance increases the literary works regarding arterial thrombosis in COVID-19. Mastering points Arterial thrombosis in the shape of Hepatic inflammatory activity severe limb ischaemia can happen in COVID-19.A large list of suspicion ought to be maintained for severe limb ischaemia, which can be a vascular crisis.Patients affected by COVID-19 pneumonia may develop tension cardiomyopathy, also known as Takotsubo syndrome (TTS), at different phases throughout the condition and with various degrees of left ventricular dysfunction. We explain three instances of TTS in COVID-19-positive customers with various clinical presentations and effects. One of these died, within the other two coronary angiography confirmed the diagnosis but had been delayed until after pneumonia resolution due to the chance of virus spread. Learning things a link between COVID-19 and cardiac involvement is highlighted.The occurrence of Takotsubo syndrome has grown with this pandemic, possibly because it is brought on by severe stress.Coronavirus condition 2019 (COVID-19) is a multisystemic problem caused by serious acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with manifestations which range from moderate upper breathing symptoms to cytokine storm causing intense breathing stress syndrome. Pancreatic exocrine tissue and endocrine islets both express angiotensin-converting enzyme 2 (ACE2), the proven receptor for SARS-CoV-2 cellular internalization. A rise in pancreatic enzymes has been increasingly recognized in patients with COVID-19, but bit is famous about the real prevalence of severe pancreatitis in this populace. We report an instance of severe acalculous pancreatitis in a COVID-19 patient. Mastering points Acute pancreatitis might be a manifestation of SARS-CoV-2 infection.Future researches must address the real effect of pancreatic participation in COVID-19 clients.In December 2019, an outbreak of an innovative new coronavirus (SARS-CoV-2) was reported in Hubei province in Asia. The disease has since spread globally additionally the World wellness company declared it a pandemic on 11 March 2020. We explain the outcome of a 65-year-old woman which clinically recovered from COVID-19 but revealed persistent infection with SARS-CoV-2 for 51 times. Discovering points an instance of persistent illness with SARS-CoV-2 is described.Some tests may select up viral RNA fragments, providing a false positive result.The quarantining of infected clients to limit feasible SARS-CoV-2 spread is important.Background Very limited information is present on pericardial effusion as a complication of COVID-19 illness. There are no reports regarding pericardial fluid findings in COVID-19 clients. Case description We describe a 41-year-old lady, with confirmed COVID-19, which served with a sizable pericardial effusion. The pericardial fluid was drained. We provide the laboratory results to improve knowledge of this virus. Discussion We believe this is basically the first such reported instance. Conclusions proposed the fluid was exudative, with remarkably high lactate dehydrogenase and albumin amounts. We hope our data supply extra understanding of the diagnosis and therapeutic choices for managing this infection.LEARNING POINTS Laboratory findings of drained pericardial liquid in a patient with COVID-19 are presented.The clinical presentation of pericardial involvement in COVID-19 disease in addition to role of echocardiography in diagnosis and management tend to be explained.We report three cases of serious thrombocytopenia during COVID-19 infection involving either cutaneous purpura or mucosal bleeding. The first investigations eliminated other causes of thrombocytopenia. Two of this patients were treated with intravenous immunoglobulins and eltrombopag, while the 3rd restored spontaneously. An excellent clinical and biological response ended up being achieved in every patients causing medical center discharge. Mastering things Immune thrombocytopenia should be considered in COVID-19-infected patients providing with thrombocytopenia.Coronavirus-related thrombocytopenia is serious and life-threatening.Despite the severity of coronavirus-related protected thrombocytopenia, data recovery could be spontaneous or achieved following immunoglobulin or platelet growth aspect administration.We report an instance of intense viral pericarditis and cardiac tamponade in a patient with COVID-19 to emphasize the associated treatment challenges, specially given the anxiety linked to the safety of standard treatment. We additionally discuss complications connected with delayed analysis in patients just who possibly might need mechanical air flow. Discovering points big pericardial effusion and cardiac tamponade should be considered in patients with COVID-19 which decompensate more after intubation and mechanical ventilation.The attributes of pericardial effusion in customers with COVID-19 are described.A effective treatment approach for severe pericarditis in an individual with COVID-19 in light of varying viewpoints throughout the security of NSAID usage is described.In December 2019, a novel coronavirus called SARS-CoV-2 had been reported to be in charge of a cluster of acute atypical respiratory pneumonia instances in Wuhan, in Hubei province, China. The condition brought on by this virus is named COVID-19 (coronavirus condition 2019). The virus is transmitted between people as well as the outbreak was stated a pandemic by the World wellness Organization (whom) on 11 March 2020. Coagulopathy is a type of abnormality in patients with COVID-19 as a result of inflammation, hypoxia, immobilisation, endothelial harm and diffuse intravascular coagulation. Nevertheless, the info on this subject are still restricted.