The c-Fos expression of the stomach, duodenum and proximate colon was also increased.

Conclusion: Ghrelin can act as central modulator of the small intestinal motility when injected into the ICV. Its excitatory effect relies on the cholinergic pathway and the central NPY pathway. Ghrelin receptor GHS-R involved in its activity. ICV administration of ghrelin could regulate the small intestinal motility through the CNS and ENS. Key Word(s): 1. ghrelin; 2. intracerebroventricular (ICV); JNK inhibitors high throughput screening 3. interdigestive myoelectric complex (IMC); 4. c-Fos Presenting Author: ARI FAHRIAL SYAM Additional Authors: DADANG MAKMUN, MURDANI ABDULLAH, ACHMAD FAUZI, CECEP SURYANI SOBUR Corresponding Author: ARI FAHRIAL SYAM Affiliations: Dr. Cipto Mangunkusumo General Hospital, Dr. Cipto Mangunkusumo General Hospital, Dr. Cipto Mangunkusumo General Hospital, Dr. Cipto Mangunkusumo General Hospital Objective: This study investigated the prevalence of malnutrition and its phosphatase inhibitor library risk factors in hospitalized adult non-surgery patients in Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia. Methods: 177 patients were hospitalized from June to November 2013. Socio-demographic characteristic was collected at the admission. Nutritional status was assessed at admission and discharge using Subjective Global Assessment, Body Mass Index (BMI) and albumin level. Results: Prevalence of malnutrition at admission

and discharge was 65.5% and 70.1% respectively by SGA, 22.6% and 24.3% by BMI, and 46.9% and 58.8% by albumin. There was no statistically significant change in malnutrition status between admission and discharge. Female patients or with anemia or tuberculosis were at risk factors of nutritional worsening. Male patients or with dyslipidemia had more improvement than others. 89.3% see more patients met their nutritional intake target but their nutritional status didn’t change significantly. Nutritional status didn’t influence the length of hospitalization but patients with worsen nutritional status had insignificant

longer period of hospitalization. SGA at discharge p Severe undernourished Mild-moderate undernourished Well nourished SGA at admission Severe undernourished 66.7% (16/24) 33.3% (8/24) 0% (0/24) 0.739 Mild-moderate undernourished 1.1% (1/92) 90.2% (83/92) 8.7% (8/92) Well nourished 1.6% (1/61) 24.6% (15/61) 73.8% (45/61) Conclusion: Prevalence of hospital malnutrition is high in Dr. Cipto Mangunkusumo National General Hospital. Although there was improvement in nutritional intake but the nutritional status at discharge didn’t change significantly between admission and discharge. Key Word(s): 1. hospital malnutrition; 2. Subjective Global Assessment (SGA) Table 1     SGA at discharge p Severe Undernourished Mild-Moderate Undernourished Well Nourished SGA at admission Severe undernourished 66.7% (16/24) 33.3% (8/24) 0% (0/24) 0.