The present study aims to evaluate the protective effect of TSG against D-galactose induced aging process in mice and its possible mechanisms of action. Our study revealed that administration of TSG improved the memory ability and regulated the body weight of mice. TSG also reduced the levels
of ROS, NO and IGF-1 and increased the levels of SOD, Ca2+ and Klotho protein in the serum. Furthermore, TSG up-regulated the expression of Klotho protein in cerebrum, heart, kidney, testis and epididymis tissues of D-galactose induced aging mice. These results suggested that TSG had a promising anti-aging effect by regulating Klotho gene. (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.”
“BACKGROUND: A packed bed bioreactor (PBBR) activated with Napabucasin in vivo an indigenous nitrifying bacterial consortia was developed and commercialized for rapid establishment of nitrification in brackish CX-4945 datasheet water and marine hatchery systems in the tropics. The present study evaluated nitrification in PBBR integrated into a Penaeus monodon recirculating maturation system under different substrate concentrations and flow rates.
RESULTS: Instant nitrification was observed after integration of PBBR into the maturation system. TAN and NO(2)-N
concentrations were always maintained below 0.5 mg L(-1) during operation. The TAN and NO(2)-N removal was significant (P < 0.001) in all the six reactor compartments of the PBBR having the substrates at initial concentrations of 2, 5 and 10 mg L(-1). The average volumetric TAN removal rates increased with flow rates from 43.51 (250
L h(-1)) to 130.44 (2500 L h(-1)) gTAN m(-3) day(-1) (P < 0.05). FISH analysis of the biofilms after 70 days of operation gave positive results with probes NSO 190 ((beta ammonia oxidizers), NsV 443 (Nitrosospira spp.) NEU (halophilic Nitrosomonas), Ntspa 712 (Phylum Nitrospira) indicating stability of the consortia.
CONCLUSION: The PBBR integrated into the P. monodon maturation system exhibited significant nitrification upon operation for 70 days as well as at different substrate concentrations MLN4924 solubility dmso and flow rates. This system can easily be integrated into marine and brackish water aquaculture systems, to establish instantaneous nitrification. (C) 2011 Society of Chemical Industry”
“Case Description-3 horses with lameness localized to the proximal aspect of the metacarpus or metatarsus.
Clinical Findings-All horses had evidence of problems that originated from the proximal aspect of the suspensory ligament (PASL), including signs of pain on palpation, positive results of diagnostic nerve blocks, ultrasonographic detection of enlargement and diffuse areas of reduced echogenicity in the proximal region of insertion of the ligament, and radiographic detection of increased mineral opacity in the proximal aspect of the metacarpus or metatarsus.