The process of harmonising methodology, sample and data collection, trans-isomer ic50 and the analysis of data will benefit from previous experiences in ADITEC and BIOVACSAFE

European projects, together with the NIAID-sponsored Systems Biology for Infectious Diseases Research Program. The working parties should agree on core recommendations and a strategic action plan to address these priorities. If funding for European Vaccine Research and Development Infrastructure materialises in 2015, a pilot phase will be launched for structuring global analyses of infectious diseases with high public health importance, such as AIDS, tuberculosis, malaria, and influenza. We would like to thank speakers at the Global Analyses Platforms Workshop: Sabin Bhuju, Carlos A. Guzman, find more Stefan H.E. Kaufmann, Helen Fletcher, David Lewis, Julie McElrath, Hans-Joachim Mollenkopf, Tom Ottenhoff, Steven Smith, Thomas Stempfl, Robert van den Berg, and Frank Verreck, without whom this manuscript could not have been written. We also thank the TRANSVAC consortium (www.transvac.org) as well as Regitze Thoegersen, TRANSVAC project leader, for her help in the organisation of the workshop and management of the project. The workshop was

supported by the EU FP7 project TRANSVAC (FP7-INFRASTRUCTURES-2008-228403). This work has received support from the EU/EFPIA Innovative Medicines Initiative Joint Undertaking ([BioVacSafe] grant n̊ [115308], the EU FP6 funded project EMVDA (LSHP-CT-2006-037506), and the EU FP7 funded projects NEWTBVAC (FP7-HEALTH-2009-241745), ADITEC (FP7-HEALTH-2011-280873) and EeURONEUT-41 (FP7-HEALTH-2007-201038). This publication reflects only the authors’ views and the European Union is not liable for any use that may be made of the information contained herein. Conflict of interest: None declared. “
“Mumps, a viral infection, can cause mild to severe symptoms or be asymptomatic. The most characteristic feature of the disease is parotitis and swelling of the salivary glands. The risk of severe symptoms and complications increases in adults [1]. Sequelae include meningitis (1–10%), encephalitis

(0–1%), oophoritis Chlormezanone (5% of female cases), orchitis (15–30% of male cases), pancreatitis (4%) and deafness (0.005%) [1] and [2]. Mumps basic reproduction number ranges from 4 to 10, which is lower than measles [3]. Based on 2004 WHO data, 38% of the countries/areas world wide use mumps vaccine in their national immunization programmes. Among these, 63% use a one dose schedule and 37% use a two-dose vaccination schedule [4]. The introduction of mumps vaccine led to a decrease in reported rates. In countries using two doses (e.g., Norway, Denmark, Finland), rates decreased to <1/100,000 population. Seroconversion rates for one dose of the Jeryl Lynn strain mumps vaccine, used in the vaccination schedule in Flanders in Belgium, ranges from 80 to 100% [5].